4-Chloro-1h-pyrrolo[2,3-b]pyridine-3-carbaldehyde (918515-16-9)

Kei te noho tenei hua (s) i runga i te kirimana APICMO.

Ko te kaha ki te whakaputa, te whakahiato me te waihanga i te rahi o 4-Chloro-1h-pyrrolo [2,3-b] pyridine-3-carbaldehyde (918515-16-9) me te pūnaha whakahaere kounga i raro i te hangahanga CGMP
ture.

Kāwai:

Whakaahuatanga

4-Chloro-1h-pyrrolo[2,3-b]pyridine-3-carbaldehyde (918515-16-9) video

Ko Janus kinases (JAKs) te mahi nui ki te whakawhitinga tohu tohu whakawhitiwhiti i waenga i te cytokine. Kua puta mai nga kaiwhakatere a JAK hei kaihautū moemoeke whai hua mo te ārai i te whakaheke o te rerenga. I whakaaturia e matou i mua atu ko te imidazo-pyrrolopyridinone 2 he kaha aukati JAK; Heoi, he iti te whakamahinga waha waha i runga i te ngoikore o te membrane. I konei, ka whakaatuhia e matou te whakarereketanga hanganga o te 2 hangarau ki roto i te 18a dipyrrolopyridine tricyclic e arotahi ana ki te whakaiti i te rohe poari (PSA), e whakaatu ana i te ngohe i roto i te vitro, te pai ake o te membrane me te koiora ora. Ko te tohu 18a i whakaatu i te kaha i roto i te tauira o te whakapapa mate pukupuku heterotopic.

Kei te noho tenei hua (s) i runga i te kirimana APICMO. Mena kei te tiro koe i tenei whārangi hei kaiwhakamahi kore-rēhitatia, ko te utu (s) e whakaatuhia ana ko te Utu Rārangi. Hei tiro i to utu, takiuru ma te whakamahi i to tau nama, ka riro hei kaiwhakamahi rēhitatia mā te whakapā atu ki tetahi o o tatou ratonga Ratonga Kiritaki. Ki te whakatakoto i tetahi tono, whakapā atu ki te Ratonga Kiritaki a APICMO.

4-Chloro-1h-pyrrolo[2,3-b]pyridine-3-carbaldehyde (918515-16-9) Specifications

CAS 918515-16-9
CAS Min% 95%
CAS Max% 100%
Tau MDL MFCD09880129
Ki te KAUPAPA KI DYWWVLQMUUZZRJ-UHFFFAOYSA-N
Ingoa Toiina, Rauemi ranei 4-Chloro-1h-pyrrolo [2,3-b] pyridine-3-carbaldehyde
Hauira Purapura Motuhēhē
Puka Puka White ki te parauri parauri
Packaging Pounamu tio
Tātai rāpoi C8H5N2OC
Taumaha Taumaha (g / mol) 180.594
Tuhinga o mua ClC1 (= C2 (C (= NC = C1) NC = C2C = O))
Tae White
Te wai kohua 372.6 ° C i 760 mmHg
anga matou 98%

4-Chloro-1h-pyrrolo [2,3-b] pyridine-3-carbaldehyde (918515-16-9) Te Haumaru me te Whakaaetanga

  • Kaua e pupuhi te puehu, te wera ranei.
  • Kia pai te horohi me te horoi kanohi.
  • Kaua e uru ki nga kanohi, ki te kiri, ki te kakahu ranei.
  • Kia mau tonu te pouaka.
  • Tiakina i roto i tetahi wahi hauora, maroke, waahi pai.
  • Me whakarite he hauora tika i te wa e whakamahia ana.
  • Whakamahia anake i roto i te hopi matomato.

WHAKATŪPATO: Ko nga korero i whakawhiwhia ki tenei pae tukutuku i whakawhanaketia i raro i nga ritenga o te ture a te Euroopu (EU) me te tika ki to maatau mohio, korero me te whakapono i te ra i tuhia ai. Ko nga korero i homai i hangaia hei awhina mo te whakahaere me te whakamahi haumaru. Kaore e whakaarohia he waahana, he kounga kounga.

4-Chloro-1h-pyrrolo[2,3-b]pyridine-3-carbaldehyde (918515-16-9) Articles

Te kitenga o nga tiwhikete dipyrrolopyridine tricyclic rite te pukapuka JAK

Ko Janus kinases (JAKs) te mahi nui ki te whakawhitinga tohu tohu whakawhitiwhiti i waenga i te cytokine. Kua puta mai nga kaiwhakatere a JAK hei kaihautū moemoeke whai hua mo te ārai i te whakaheke o te rerenga.

Te Biomiora me te Maimoatanga 2017

Ko te tohu me te aromatawai koiora o nga korero a pyrrolo [2,3-b] pyridine rite nga kaitautoko antiproliferative me to ratou taunekeneke ki te DNA wheehe DNA

He raupapa o toru tekau e rua pyrrolo pūrākau [2,3-b] analogues pyridine synthesized, āhuatanga (1H NMR, 13C NMR ko MS) me te aro mātai cytotoxic o enei rāpoi ngota kawea i roto i runga i te rōpū o toru ngā rārangi pūtau pukupuku tangata tae atu A549

Ko te Rangahau o te Maturanga Rangahau o te Iwirangi a 2016

Ratonga Hangarau:

Kei to tatou kapa o nga kaitaiao nga wheako ki nga waahanga katoa o te rangahau, tae atu ki te Life Science, Te Hangarau Rauemi, te Hinengaro Hinairo, te Chromatography, te Tatauranga me etahi atu.

4-Chloro-1h-pyrrolo [2,3-b] pyridine-3-carbaldehyde (918515-16-9) Whakahua Puku & Tauira:

Me nui ake nga waahanga mo to whakawhanaketanga, mahi mahi, rangahau ranei?


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